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Semaglutide has two amino acid substitutions compared to human GLP-1 (Aib8, Arg34) and is derivatized at lysine 26
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![PDF] Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial](https://figures.semanticscholar.org/898978c1b0543b943d605e293f5296fb7568cee7/12-Table3-1.png)
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