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How to calculate your Synedica Retatrutide dosage Synedica Retatrutide is administered as a once-weekly subcutaneous injection following the gradual escalation schedule from Phase 3 clinical trials: Weeks 1–4: 2mg once weekly Weeks 5–8: 4mg once weekly Weeks 9–12: 8mg once weekly Week 13 onward: 9mg or 12mg once weekly (maintenance) The 12mg maintenance dose consistently produces the highest Synedica Retatrutide weight loss results across all clinical data published to date
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