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However, hypoglycemia can become a serious risk if GLP-1s are taken with medications that lower blood glucose, such as sulfonylureas or insulin
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In the DECLARE trial [see Clinical Studies (14.3)], mean changes from baseline after 4 years were 0.4 mg/dL versus -4.1 mg/dL for total cholesterol, and -2.5 mg/dL versus -4.4 mg/dL for LDL cholesterol, in FARXIGA-treated and the placebo groups, respectively