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A weak potentiation of compound 2โ€“mediated cAMP production (or surrogate readouts such as cAMP response elementโ€“driven luciferase reporter) has also been reported for interaction of this ligand with truncated forms of exendin, including exendin 5โ€“39 , exendin 7โ€“39 , and exendin 9โ€“39 , even in the absence of any measurable intrinsic activity (Coopman et al., 2010

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