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A weak potentiation of compound 2โmediated cAMP production (or surrogate readouts such as cAMP response elementโdriven luciferase reporter) has also been reported for interaction of this ligand with truncated forms of exendin, including exendin 5โ39 , exendin 7โ39 , and exendin 9โ39 , even in the absence of any measurable intrinsic activity (Coopman et al., 2010