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The exception is highly potent peptides (like semaglutide) where tiny doses of concentrated solution are intentional and where specialized fine-gauge syringes may be used

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Comparative studies with liraglutide, exenatide, dulaglutide, tirzepatide, and retatrutide use semaglutide as the standard active comparator, making it one of the most frequently cited research peptides of the past decade