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Comparative studies in GLP-1R knockout and wild-type mice have shown that GLP-1-dependent signaling alters gut microbial composition, with increased abundance of Gammaproteobacteria and Firmicutes, and reduced levels of Actinobacteria and Bacteroidetes
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Surveying a representative sample of 8,793 Americans, the researchers found that 11.8% have used GLP-1 agonists and 14% say they are interested in using the drugs
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