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Ozempic constipation: How to treat it and prevent another bout - Oshi Health
How GLP-1 secretion occurs so rapidly is still unclear but may be due to the presence of some L-cells in the upper jejunum (31)
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The drug has been studied in human trials, including a Phase 2 trial published in The Lancet in 2008 and a Phase 3 trial in 372 patients in Mexico, but a dedicated cardiovascular outcomes trial that US and EU regulators would expect has not been run