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A randomized flow trial across 28 countries examined the effects of weekly 1.0 mg subcutaneous semaglutide on T2DM and CKD patients ( n = 3534, mean age 66.6 years) using an 8-week dose escalation regimen (0.25–0.5 mg/week for four weeks, followed by 1.0 mg/week for another four weeks)
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