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Only 0.5–1% of the granules belong to the readily releasable pool (RRP), from which only a subset, the immediately releasable pool (IRP), is located in the vicinity of the Ca 2+ channels and is released with minimal time delay upon opening of the Ca 2+ channels [508]

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Any unexplained inconsistency may undermine the attribution and reliability of the affected data and may warrant an expanded assessment of other products, systems, analysts, and records