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GLP-1 receptor agonism potentiates glucose-dependent insulin secretion and signals through hypothalamic circuits governing food intake
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During the last 2 weeks of the titration periods in those 12 participants, semaglutide led to a higher time in range by 4.3 percentage points (5.5, P = 0.02), lower insulin usage by 12.2 U [−16.2, −5.4] ( P = 0.008) and lower carbohydrate intake by 50 g (35
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