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Are GLP-1s Safe for Seniors? Benefits & Risks | MDWatch

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semaglutide) Ozempic produces greater weight loss (10-15%) compared to Trulicity (3-5%) Ozempic provides better blood sugar control, with approximately 0.4% greater HbA1c reduction in head-to-head trials Both have proven cardiovascular benefits, with similar reductions in major cardiovascular events Side effects are similar since both work through GLP-1 pathways (primarily gastrointestinal) Trulicity’s device is often considered easier to use for patients who struggle with pen injectors Neither is FDA-approved specifically for weight loss