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Tirzepatide is processed primarily by the liver and doesn't directly stress the kidneys, though GLP-1 medications can affect kidney function markers in people with certain conditions

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ATP assays By time-lapse microscopy INS-1 832/3 cells were seeded in 35-mm glass-bottom dishes (MatTek) and transfected with the ATP biosensor cyto-Ruby3-iATPSnFR1.0 100