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63 Moreover, GLP-1RA treatment modulates the expression of additional barrier-associated genes, including IL-33, mucins, and CCL20—although the direction and magnitude of regulation vary depending on the colitis model, disease timepoint, and genetic background, complicating interpretation
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“Cuanto más restrictiva sea la dieta, más va a resistirse el cuerpo y peor va a ser la adaptación metabólica, por eso gente que ha hecho muchas dietas, comiendo poco, engordan, porque el metabolismo basal quema una tercera parte de lo que tiene que quemar”, explica Ciudin