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The DNA sequence may also be prepared by polymerase chain reaction using specific primers, for instance as described inUS 4,683,202or Saiki et al., Science 239 (1988), 487 - 491
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Comorbidities (hypertension, stroke, acute myocardial infarction, chronic kidney disease, dyslipidemia, and liver disease) were defined using ICD-10 codes, prescription data, and national health screening examination data