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Semaglutide had been approved for both diabetes and obesity treatment, while tirzepatide was only approved for obesity in November of 2023 ( Regarding the time of onset, our study showed that the median time to onset of the overall GLP-1 RA AEs was 31 days (IQR = 7–145.4 days)
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1 However, experience and clinical evidence consistently show that these medications are not magic bullets