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AD Alzheimer's disease, PD Parkinson's disease, TNF-ฮฑ tumor necrosis factor-alpha, IL interleukin, PI3K phosphoinositide 3-kinase, Akt protein kinase B, PGC-1ฮฑ peroxisome proliferator-activated receptor gamma coactivator 1-alpha, mTOR mechanistic target of rapamycin, CREB cAMP response element-binding protein, BDNF brain-derived neurotrophic factor Safety considerations and patient selection GLP-1 receptor agonists have a well-defined safety profile
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In some studies, Semaglutide GLP-1 has shown greater effectiveness in lowering blood glucose and supporting weight loss than Liraglutide