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Artificial sweeteners, especially sugar alcohols like sorbitol and xylitol, add to the osmotic load in the colon and worsen diarrhea
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In a pre- and postnatal development study in pregnant Sprague Dawley rats, SNAC was administered orally at 1,000 mg/kg/day (exposure levels were not measured) on Gestation Day 7 through lactation day 20
