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Although this class of drugs, called glucagon-like peptide-1 or GLP-1, have been around for more than 17 years, with the first one, Byetta®, approved in 2005, it is only recently that the class has made a big name for itself with the introduction of the popular once-weekly diabetic drug, Ozempic ® , and the equally popular obesity drug, Wegovy ® (the same drug as Ozempic but with a different dose)
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When metformin does produce weight reduction, it averages 2-3 pounds over six months—substantially less than the 15-20 pound range semaglutide achieves in the same timeframe
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