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The index date was defined as 12 months after the date of BMS or initiation of GLP1-RA, in order to allow a lag-time for the assessment of the study outcome, hence avoiding immortal-time bias

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The powder is also swallowed with a drink, otherwise known as the “toss and wash method.” Kratom powder is added to smoothies, cocktails, caffeinated beverages, and even cough syrup