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As GLP-1 medications enter the global spotlight in elite sports (and the @olympics), nuance matters. In @medpage MedPage Today, our own Dr. Stephen Henry explains why these drugs may reduce performance—not enhance
Differences between groups were compared via two-tailed unpaired t tests for two groups, one-way analysis of variance (ANOVA) followed by Dunnett’s multiple comparison test for multiple groups, or two-way repeated-measures ANOVA followed by the Bonferroni multiple comparison test for multiple groups and time courses
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Transdermal estradiol, delivered through patches or gels rather than oral tablets, bypasses the liver entirely, avoiding the first-pass hepatic metabolism that oral estrogen undergoes and that is associated with increased clotting factor production and thrombotic risk
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