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although GRADE scores indicate low to moderate quality for most of these comparisons, incretin-based therapies seem to be an advisable option for long-term treatment to preserve β-cell function ( In T2D patients eligible for GLP-1 therapy, HOMA-IR before starting the treatment could be an indicator of patients’ “phenotype” as defined by Ahlqvist et al

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Medical advice: Sometimes, healthcare providers may recommend pausing due to concerns like dehydration, pancreatitis, or gallbladder issues