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Tirzepatide and Liraglutide microdosing Similar to semaglutide microdosing, tirzepatide microdosing is an off-label practice of taking a weekly dose of tirzepatide (brand names Mounjaro or Zepbound) that is lower than the FDA-approved 2.5 mg starting dose to reduce common gastrointestinal side effects and potentially lower the cost by making the medication last longer