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Serious but Rare Complications Though uncommon, serious side effects include: Pancreatitis (inflammation of the pancreas) from dehydration Acute kidney injury Possible in animal studies thyroid C-cell tumors GLP-1s are not recommended for individuals with a personal or family history of Medullary Thyroid Carcinoma (MTC) or MEN2 syndrome

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Novel, in-vivo and in vitro data suggest that exenatide, a GLP-1 receptor agonist, may represent an ideal therapy for IIH through rapid reduction of CSF secretion at the choroid plexus, lowering ICP in addition to its weight loss properties