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Titration schedule After the initial 4 weeks at 2.5mg, the standard tirzepatide titration schedule increases the dose in increments: Weeks 1-4: 2.5mg weekly Weeks 5-8: 5mg weekly Weeks 9-12: 7.5mg weekly Weeks 13-16: 10mg weekly Weeks 17+: 12.5-15mg weekly (if needed) Not everyone needs to reach the maximum dose
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