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The dose-limiting toxicities of free lanifibranor (weight gain, edema, anemia, fluid retention) are the consequences of saturating PPAR receptors throughout the body, including in tissues where activation is unwanted
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Unlike injectable forms of GLP-1 medications, oral semaglutide offers a convenient pill form that can be taken once daily
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![PDF] Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide](https://figures.semanticscholar.org/594349790d0e9a09f8b5843f2782af9cfaaa7bf4/37-Figure3-1.png)
