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Firms seeking approval for generic versions of brand-name drugs must file paragraph IV certifications in cases when the brand-name reference drug has active patents listed in the Orange Book

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Still, it’s important to know when a digestive slowdown moves from “annoying” to “needs professional attention.” According to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), you should reach out to your healthcare provider if you experience any of the following: You have not had a bowel movement in more than 3–4 days

It’s also approved to treat moderate to severe obstructive sleep apnea (OSA) in adults with obesity.