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In a substudy of the LEAN trial that included 14 patients, liraglutide significantly reduced low-density lipoprotein (LDL)-cholesterol, ALT, serum leptin, adiponectin, and CCL-2 concentrations (all p 10%), the 24-week effect of treatment with 10 μg exenatide and insulin glargine twice daily was compared [48]
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