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Regarding the vascular system, continuous infusion of the GLP-1 analog exendin-4 reduced monocyte adhesion to aortic endothelial cells, associated with a reduction in atherosclerotic lesion size in non-diabetic C57BL/6 and ApoE −/− mice

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A prospective clinical study from Spain found that besides controlling blood glucose (fasting blood glucose and glycosylated hemoglobin), LIXI can also improve blood lipids, especially total cholesterol and triglyceride (68)