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The protein kinase A (PKA) pathway supports NO–mediated smooth muscle relaxation via cAMP signaling [184], whereas the Hippo–YAP1 axis regulates endothelial integrity, glucose metabolism, and fibrosis [185]
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[171] preliminarily showed the excellent efficacy of triple agonists in reversing fatty liver disease in mouse models
![PDF] The Effects of Dual GLP-1/GIP Receptor Agonism on Glucagon Secretion—A Review](https://figures.semanticscholar.org/0fd860de34d08549f35b05af15ce08d651210045/4-Figure1-1.png)
