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Unfortunately, it is difficult to assess potential sex differences in pharmacokinetics and tolerability of, for example, semaglutide, as a large fraction of the available data was either tested exclusively in male human, primate, or rat subjects (82) or not presented disaggregated by sex (83, 84)

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reuteri resulted in a 76% increase in glucose-stimulated GLP-1 and GLP-2 and a 49% rise in insulin compared to placebo [9]