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More than 6 million patients in the US initiated GLP-1 use between 2021 and 2025. The proportion of prescriptions without documented clinical indications rose steadily over that time, reaching roughly 0.74% by
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For example, a 72-week phase II trial involving 320 patients with MASH, reported MASH resolution rates of up to 59% at the highest dose of 0.4 mg daily as compared to 17% in the placebo group
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