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Dipeptidyl peptidase 4 inhibitors with gliptin-like structures, based on approved and published data, are generally classified into three groups: (a) Compounds with a pyrrolidine as the S 1 -binding segment connected by an aminoacyl spacer, (b) those containing trifluorophenyl derivatives as the S 1 -binding segment with an α-aminobutanoyl spacer, and (c) structures featuring pyrimidine-2,4-dione or its analogs as the S 1 -binding segment
weight management
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Glucocorticoid treatment in SLE is associated with infections, comorbidities and mortality — a national cohort study
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