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GIP activation: Enhances insulin secretion beyond GLP-1 alone Appears to improve fat metabolism and reduce visceral adiposity May enhance satiety signaling through different neural pathways than GLP-1 Modulates lipid handling in adipose tissue The clinical result of dual agonism is measurably greater weight loss and slightly better glycemic control in head-to-head trials (see section 5 below)

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GLP-1 drugs, mimicking the glucagon-like peptide-1 hormone, quell appetite by amplifying fullness and slowing digestion, poised to redefine not only physiques but also food markets, dairy included