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TNF-α levels decreased by an average of 28% (p IL-6 levels decreased by an average of 24% (p The study found a 31% reduction in cartilage degradation markers (p The researchers used regression analysis to show that GLP-1 receptor activation has a strong negative relationship with inflammatory cytokine levels, which they measured at r = -0.68
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These findings support the successful translation of neuroprotective and anti-neuroinflammatory properties from cellular to animal studies for this promising drug
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