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Oprah Winfrey says she will have to be on GLP-1s for life after trying to "beat the medication" by stopping for 12 months and gaining back 20 pounds : r/Fauxmoi

These insights extend to gut health, highlighting genetic influences on microbial balance, inflammation, and nutrient absorption

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Unlike GLP-1RAs, DPP-4i have no effect on gastric emptying or weight loss