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Ma il ruolo forse più interessante riguarda la regolazione dell’appetito : agendo sul sistema nervoso centrale, il GLP-1 riduce la sensazione di fame e aumenta quella di sazietà, aiutando chi ha difficoltà a controllare la quantità di cibo assunto
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Even if this translates perfectly to humans (which in-vitro findings rarely do), a 38% reduction in DPP-4 would modestly extend GLP-1's half-life from about 2 minutes to perhaps 3-4 minutes
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