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👀 Implications for clinical practice: If you manage T2D patients, now is the time to ask: “Have I considered liver health in this patient?” “Have I screened for advanced fibrosis?” “Is my choice of glucose-lowering therapy optimised for both glycaemic and hepatic benefit?” Even in settings where hepatology referrals are limited, simple non-invasive tests (e.g., FIB-4) may help stratify risk

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3 Strategies like enteric coatings to bypass gastric acid, local pH modulation and enzyme inhibitors to deactivate intestinal proteases, muco-penetrating or muco-adhesive carriers, and transient permeation enhancers to increase membrane fluidity are used to mitigate these barriers