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However, the activity only becomes apparent once the degradation of DPP-4 has been prevented, as the majority of GLP-1 reaching the kidneys has already been processed by DPP-4
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is supported by a Banting and Best Diabetes Centre Chair in Incretin Biology, a Sinai Health-Novo Nordisk Foundation Fund in Regulatory Peptides and operating grants from CIHR and Diabetes Canada-Canadian Cancer Society
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