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Preclinical evidence supports the role of GLP-1RAs in alleviating neuropathic pain through the modulation of microglial activity, inflammatory cytokine production and β-endorphin release [63, 65, 68, 70–74]
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Since then, he notes that both the FDA and European Medicines Agency (EMA) have investigated it and landed on the same conclusion: They don’t think there’s a cause and effect
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