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In the STEP 1 extension, participants who discontinued semaglutide regained a substantial proportion of lost weight within one year, with parallel worsening of cardiometabolic improvements
Do not use this product if you have had a bariatric surgical procedure.
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![PDF] Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide](https://figures.semanticscholar.org/594349790d0e9a09f8b5843f2782af9cfaaa7bf4/37-Figure3-1.png)
