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Why are GLP-1 agonists being used to treat patients with nonalcoholic fatty liver disease? | AASLD

14 Insulin secretion after meals is further accentuated by release of the incretin hormone, glucagon-like peptide-1 (GLP-1), from intestinal neuroendocrine L-cells

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A 1,3-diolein-based lipidic promoiety (IN-4) was synthesized and conjugated to curcumin, betulinic acid, and oleanolic acid to generate three representative LDCs: CUR-PRO, BA-PRO, and OA-PRO