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“Data from clinical trials have been very promising on this front, but it’s reassuring to see that these medications are also useful in clinical settings that aren’t as highly controlled as clinical trials.” White said future research should analyze predictors for weight loss in people with diabetes to better understand who would best respond to a GLP-1 agonist and examine changes in body weight for adults who are fully adherent to GLP-1 therapy
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The approval was backed by data from the Phase II DESTINY-PanTumor02 trial, which enrolled nearly 470 patients with HER2-positve solid tumors
