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GLP-1 Receptor Agonists Improve HS in Patients With Obesity
Outside the PNS, expression of peripherin was highest in the ileum, but with more than 31-fold lower expression relative to the trigeminal ganglion, and with even lower to absent expression in the cerebellum, cerebral cortex, midbrain, kidney, testis, pituitary, adrenal gland, stomach, duodenum, jejunum and colon (Extended Data Fig
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The American College of Rheumatology’s 2025 annual conference (ACR Convergence 2025) added to this picture, with data suggesting that patients on GLP-1 drugs had fewer rheumatic disease flares and that those with osteoarthritis saw greater improvements in pain and function compared to those on SGLT2 inhibitors, another diabetes drug class [11]
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