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In line with US Food and Drug Administration (FDA) and European Medicines Agency (EMA) guidelines for studies in subjects with renal impairment [18, 19], the aim was to recruit normal and impaired renal function groups which were comparable with respect to sex, age and body weight as far as was possible
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The safety profile of dulaglutide mirrors that of the broader GLP-1 receptor agonist class, with gastrointestinal adverse events representing the most common treatment-emergent effects
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