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Grey-market peptides are becoming mainstream, but evidence of their effectiveness is thin or non-existent
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Retatrutide (“GLP‑3”) is a triple agonist adding glucagon for energy expenditure and fat burning, with phase 2/3 trials showing 24–28.7% average weight loss over 48–68 weeks—potentially double semaglutide’s impact. What weight loss results have retatrutide shown in trials
